Tag Archive for: pesticide

Yes, the Nutrients Are There

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My question is whether you get any nutrients besides sugar and fat from those marshmallow-covered yams or the green beans swimming in condensed mushroom soup and topped with fried onions from a can. The research on cooking techniques and retention of vitamins, minerals, and phytonutrients in vegetables and fruits is not extensive but overall, the answer is yes. Here’s a synopsis of what I found.

Cooking and Nutrients

The vitamin that seems to be lost regardless of whether it’s boiled, microwaved, or sauteed is vitamin C. Microwaving seems to preserve the most nutrients, but close to 90% of vitamin C is lost.

For some nutrients, such as beta-carotene and other carotenoids, starting with fresh vegetables as opposed to frozen seems to help retain nutrients. The amounts of carotenoids in carrots, sweet potatoes, pumpkins, and yams seem to increase when they are cooked. The same may be true in greens such as spinach and collard greens. Adding bacon doesn’t appear to cause any issues. Using nuts and fruit to make the veggies more attractive can add nutrients as well; for added color and texture, we added slivered almonds and pomegranate seeds to the brussels sprouts with parmesan—yum!

Casseroles may provide the best cooking style when appropriate. Whatever minerals leech out of the vegetables or fruits will be retained in the liquid of the casserole.

Surprise Finding

Cooking may reduce the amount of pesticide residues in vegetables. It’s nice to know that blanching, boiling and even stir frying may decrease residues by 10–80%. The research didn’t look at the liquid used for blanching or boiling, so we don’t know whether it’s a chemical change in the structure of the pesticide or it just leaches it out. Still, it was a welcome surprise.

The Bottom Line

Traditional holiday foods do retain beneficial nutrients. They can’t offset all the fat and sugar that were added, but we’re getting some of the vitamins, minerals, and phytonutrients the foods contain. To me, the real lesson is that the way the food is prepared may help you eat more vegetables and fruit. Steamed green beans? Yecch. But covered in a sauce? Maybe that will help get more vegetables into your picky eaters. As long as we control the amount and the frequency, we can feel good about eating holiday foods all year long.

What are you prepared to do today?

        Dr. Chet

References:
1. Food Sci Biotechnol. 2017 Dec 12;27(2):333-342
2. Nutr Bull. 2022 Dec;47(4):538-562.  doi: 10.1111/nbu.12584.
3. Foods. 2022 May 18;11(10):1463. 

The Bottom Line on Chlorpyrifos

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Today’s health news is full of controversy, some based on reality but most not. Typically, I would have concluded that the op-ed piece was just that: an opinion that exaggerated the facts to put forth a specific point of view. But before I go further, let me be clear: I’m not in favor of any pesticides if they can possibly be avoided. But we also live with the necessity of feeding billions of people and can’t afford to lose crops; we judge fruits and vegetables by appearance because we no longer know the grower personally. There may be some chemicals that are necessary to get that done. The issue comes down to the question of safety. That’s where all the research I read comes into play.

PON1

When I attempted to find the statistics on chlorpyrifos, I came across a large body of research that examined how organophosphates such as chlorpyrifos were eliminated by the body. The paraoxonase 1 gene (PON1) makes enzymes that help the liver and kidney detoxify chemicals such as chlorpyrifos (1). Research on several groups of subjects show that if exposure doesn’t exceed the detoxification capacity of the body, the current tolerance limits are safe for most people.

The problem is similar to what we find in other genes: there are mutations of the PON1 gene that affect the ability of the gene to produce enough enzymes to detoxify the body effectively (2). If the body isn’t able to detoxify itself, the amounts of chlorpyrifos in the body can exceed safe levels. That means that those with the PON1 mutation may be most at risk for chlorpyrifos exposure.

Or maybe not. Again it comes down to exposure. In a study of farm workers chronically exposed to chlorpyrifos, there was no difference in the gene mutations with the ability to detoxify (3). In another study, blood samples with normal and mutated PON1 genes were exposed to high and low levels of chlorpyrifos; the high levels negatively affected the mutated version of the PON1. The low levels, reflective of typical environmental exposure, showed no negative effect (4).

The issue is one of exposure, whether someone has the PON1 mutation or not. Research shows that mothers and children who live in agricultural areas are more at risk to having higher levels of organophosphates in their systems. What isn’t clear is the impact of genetic mutations that result in health issues.

In a recently published paper, researchers found that infants born to mothers with the PON1 mutation and exposed to environmental organophosphates had smaller head circumferences relative to size (5). Whether that translates to reduced IQ or other neurological conditions remains to be seen.

The Impact of Nutrients on Chlorpyrifos Exposure

Several studies demonstrated potential benefits of nutrients on chlorpyrifos exposure. PON1 is also related to cardiovascular health. In a study of over 400 subjects, those subjects with a mutated version of the PON1 gene and with higher amounts of polyphenols from fruit and vegetable intake did better in measures of cardiovascular risk such as high cholesterol (6).

In another study, subjects who consumed organic honey as a supplement experienced less damage and better DNA repair after chronic exposure to organophosphates (7). The polyphenols in the honey were identified as the primary factor related to the repair process.

Finally, in a study of pregnant women and their offspring, researchers examined the affect of folic acid intake in those women who were and were not exposed to organophosphates (8). Those who had a greater than 800 mcg intake during their first month of pregnancy when exposed to pesticides had fewer children with autism spectrum disorder.

While all of this research is recent, it seems clear that nutrients can have a positive impact on people who are exposed to organophosphates such as chlorpyrifos and other pesticides.

The Bottom Line

When I began the research on one statement in an op-ed piece, I never imagined it would end up here, but you go where the research takes you. While this research trip took us to the USDA, the PON1 gene, and some nutrients that can be protective against exposure to chlorpyrifos, one fact I was unable to find was that we are exposed to excess amounts from the fruits and vegetables we eat. That statement in the op-ed was false. But in that journey, we learned a lot. It’s not where you begin; it’s where you finish.

Four final points:

  • I think the ban on chlorpyrifos should be reinstated. Tolerance limits doesn’t mean it’s safe for everyone, and not every harmful impact has been examined.
  • Whether the discontinuance is reinstated or not, eat your fruits and vegetables after you wash them carefully. The value of the nutrients for your health exceeds any risk from chemicals that may be present.
  • Add some extra insurance by taking your supplements.
  • If you’re a golfer, you may want to learn the course’s pesticide schedule and avoid those days.

What are you prepared to do today?

Dr. Chet

 

References:
1. www.ncbi.nlm.nih.gov/gene/5444.
2. Toxicology. 2013 May 10;307:115-22. doi: 10.1016/j.tox.2012.07.011.
3. Toxicol Appl Pharmacol. 2012;265(3):308-15. doi:10.1016/j.taap.2012.08.031.
4. Toxicol Lett. 2014 Oct 1;230(1):57-61. doi: 10.1016/j.toxlet.2014.07.029.
5. Ann Glob Health. 2016; 82(1): 100–110. doi:10.1016/j.aogh.2016.01.009.
6. J Transl Med. 2016 Jun 23;14(1):186. doi: 10.1186/s12967-016-0941-6.
7. Mol Nutr Food Res. 2016 Oct;60(10):2243-2255.
8. Environ Health Perspect. 2017 Sep 8;125(9):097007. doi: 10.1289/EHP604.

 

Chlorpyrifos: Checking the Statistics

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When I began my research, the one statistic I had to check was that fruits and vegetables contained 140 times the amounts safe for 1–2 year old (1). Was it sensational or based in science? I’m good at what I do, but I couldn’t find it anywhere. I did find a lot of interesting studies but not that. I finally wrote the author of the op-ed piece; I didn’t get an answer from him, but I got one from his research assistant who gave me the precise source of the statistic.

Sure enough, page six of the EPA report (2) listed the claim of 140 times the safe amount—except that was not exactly what the EPA found in fruits and vegetables. It was a hypothetical amount that applied to the 100th percentile of potential intake. I spent several days and examined dozens of related articles just to figure out how the number was derived. What I can tell you is that it does not reflect what the exposure may be on the fruits and vegetables children or adults actually consume.

I found that number because every year, the USDA publishes a summary of the pesticides found on and in foods as part of the Pesticide Program (3). This report is the basis for the Environmental Work Group’s Dirty Dozen vegetables and fruits you shouldn’t eat. I examined the data for chlorpyrifos, and here’s what I found:

  • 9,843 samples of 19 fruits and vegetables were analyzed
  • 84 samples contained chlorpyrifos
  • 1 sample out of 84 exceeded the EPA tolerance levels

The amounts actually tested by the EPA did not come close to what was reported in the op-ed piece or what was published in the Registration Review by the EPA Committee. But I found a lot more than that, and I’ll get to that on Saturday

What are you prepared to do today?

Dr. Chet

 

References:
1. Nicholas Kristof. The New York Times. October 28, 2017.
2. EPA. 11/2016. Chlorpyrifos: Revised Human Health Risk Assessment for Registration Review.
3. www.ams.usda.gov/datasets/pdp

 

A Pesticide Story

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It’s not where you begin; it’s where you end up.

Pesticides are designed to kill bugs on our farms, in our homes, and in our yards. One such pesticide is chlorpyrifos, an organophosphate pesticide. It’s a very effective nerve toxin that will essentially kill anything with a nervous system if the exposure is high enough. It was eliminated for in-home and yard use years ago but is still used as a farm pesticide as well as on golf courses and other open areas.

Paula forwarded an op-ed piece from the New York Times that talked about a recent EPA decision to ban this pesticide for all uses; the decision was overturned by the current administration. After years of investigation by numerous scientists that concluded that chlorpyrifos was potentially too toxic, use is going to continue. One statistic in the article that stuck out to me was that the EPA had found levels on fruits and vegetables at levels 140 times what was determined to be safe for children 1–2 years old.

I can’t feed my grandson Riley vegetables and fruits that can harm him, so I had to check that out. I don’t care about the political intrigue; I’m concerned about what’s safe for you as readers and your families as well as my family. But as I said in my opening sentence, where I began is not as important as where I finished. This week will show how complicated eating in the 21st century can be.

What are you prepared to do today?

Dr. Chet

 

References: Nicholas Kristof. The New York Times. October 28, 2017