Tag Archive for: diet

Blue Zones: Eat Reasonably

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As I continued to consider the four areas that make up the health habits related to living to 100, I would have thought that nutrition was going to be the key. After much reflection, it’s not. However, it doesn’t mean you should live on a diet of sweets, deep-fried foods, and a lot of ultra-processed foods.

Eat a Selective Plant-Based Diet

Do I mean you have to be a vegan? No. But as North Americans, we just don’t eat very many minimally processed vegetables. By minimally processed I mean you cut them up, season to taste, and cook. It can be stews, soups, side dishes, or whatever.

While the types of plant-based foods vary by culture, there are several foods in common:

  • Beans, lentils, and nuts of all types are an important source of fiber and protein. Soups and salads are perfect delivery systems, but so is chili—as spicy as you like it.
  • Root vegetables are important: potatoes, especially sweet potatoes and yams, carrots, and purple yams called ube.
  • Green, leafy vegetables: lettuces, cabbages, and greens of all types, such as coleslaw or collard greens with bacon. Eat some every day.
  • Lean meats for additional protein.
  • Wine, if you drink it, even though it’s a processed grape.

Make those the foundation of your diet along with healthy oils such as olive oil and some whole grains, and that’s it. Remember, this isn’t a weight loss program; it’s a way to eat for life.

Two More Important Points

Don’t overeat. Eat just enough and no more. The Okinawans eat to feel 80% full and that’s where they stop.

Get to a normal body weight, no matter what it takes or how long it takes, and stay there. It’s easier to move around if you’re leaner, and you’ll have fewer complications of degenerative disease.

The Bottom Line

What you eat is important to live well, whether to 100 or not. It’s not difficult, but it may force you to think about how you can do that until it becomes a habit. The sooner you figure that out, the more time you get to live well. Next week I’ll finish this up with the most important secret of living to 100, Blue Zones or not. It surprised me.

What are you prepared to do today?

        Dr. Chet

Make Every Bite Count

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You’re eating vegetables, fruit, whole grains, dairy, proteins foods, and oils, and you’re staying within calorie limits for a healthy BMI. Does this sound abnormal to you? Sure, we can quibble about the need for dairy or the percentage of carbohydrates, but the Dietary Guidelines for Americans (DGA) are reasonable, and they’re almost exactly the same as when they were first written almost 50 years ago.

Is there a recommendation to “make sure you eat every cookie, candy, pie, and pasta in mass quantities every day” anywhere to be found? No. Is this a responsible approach to get the nutrients you need? Yes. The guidelines also recommend foods that are specific to cultures and ethnic groups and a variety of cooking styles.

Compare that with the keto recommendations of severely restricting carbohydrates, or veganism restricting animal products of any types, or the paleo diet restricting every grain for some unverifiable theory about what people ate in the Paleolithic era. Which sounds stranger to you now?

DGA Limitations

The DGA also includes these recommendations:

  • Added sugars: Less than 5% of calories per day starting at age 2. Avoid foods and beverages with added sugars for those under 2.
  • Saturated fat: Less than 10% of calories per day starting at age 2.
  • Sodium: Less than 2,300 milligrams per day, and even less for children younger than 14.
  • Alcoholic beverages: Adults of legal drinking age can choose not to drink, or to drink in moderation by limiting intake to two drinks or less in a day for men and one drink or less in a day for women, when alcohol is consumed. Drinking less is better for health than drinking more.

The Bottom Line

Is there a lot to criticize about the DGA? Not really. Most people who do are actually criticizing the Western-style diet and the food selections people make when eating that way. Nowhere does it say that we should eat ultra-processed foods to fulfill the carbohydrate recommendations. As I’ve said, I like Cheetos and peanut butter cookies about as much as the next person, but those are not something to eat on a regular basis. As the occasional snack in small amounts, sure. But as a regular part of the diet? No. The guidelines can recommend, but they can’t control manufacturers to the extent that they produce only foods that fit within the DGA. That choice on how to follow the guidelines is laid upon your shoulders for you and your family.

Now that you know what the guidelines actually say, maybe you can make better decisions about what you want to put into your body and in what quantity. Remember the tag line of the DGA? Make every bite count. Your body, your choice.

What are you prepared to do today?

        Dr. Chet

Reference: Dietary Guidelines for Americans, 2020-2025 Executive Summary

What Are the Dietary Guidelines for Americans?

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“Make every bite count.” You might think that phrase came from one of the many nutritional gurus on the Internet or in the thousands of books written about the best way to eat. Fact is, that’s the tagline from the USDA Dietary Guidelines for Americans 2020-2025 (DGA). Do you know what’s contained in those guidelines? We often see criticism of the DGA by those gurus, but they seem to be obsessed only with the supposed high carbohydrate levels and how bad that is for us. I thought we should review the guidelines so we understand the facts.

The most important change I see is an emphasis on nutrition in a baby’s first year and then at various life stages. The main focus, whatever the age group, is to focus on meeting food group needs with nutrient-dense foods and beverages, and stay within calorie limits. Two concepts there that we shouldn’t miss: food first and don’t overeat for your health and activity pattern. A healthy dietary pattern consists of the same nutrient composition in the foods and beverages across all food groups, in recommended amounts, and within calorie limits.

Here are the core elements that make up a healthy dietary pattern:

■  Vegetables of all types: dark green; red and orange; beans, peas, and lentils; starchy; and other vegetables

■  Fruits, especially whole fruit

■  Grains, at least half of which are whole grain

■  Dairy, including fat-free or low-fat milk, yogurt, and cheese, and/or lactose-free versions and fortified soy beverages and yogurt as alternatives

■  Protein foods, including lean meats, poultry, and eggs; seafood; beans, peas, and lentils; and nuts, seeds, and soy products

■  Oils, including vegetable oils and oils in food, such as seafood and nuts That’s it. Sounds reasonable to me—how about you? I’ll talk about what is unreasonable and the most important recommendation of the DGA on Saturday.

What are you prepared to do today?

        Dr. Chet

Reference: Dietary Guidelines for Americans, 2020-2025 Executive Summary

Phytonutrients: Diet or Supplements?

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The study that we looked at this week demonstrated that flavonoid intake is related to socioeconomic status. It also demonstrated that most of that difference comes from the consumption of tea. All well and good.

What stood out to me was the lack of phytonutrient intake. While there were some small differences in the other flavonoids besides flavan-3-ols, the total intake of flavonoids was low. Even though we’re talking about just one class of phytonutrients, the total flavonoid intake minus the flavonoids from tea was about 140 milligrams per day. That’s reflective of a poor diet that does not include as many sources of phytonutrients as it should: not enough vegetables, fruit, beans, nuts, and others. And it hasn’t changed in the six years of the study. Most people still don’t eat enough plant-based foods to do themselves any good.

Supplements: An Insurance Plan

The study demonstrated the need for the regular use of supplements containing plant concentrates. A plant concentrate is the plant or its fruit or its root or its leaves, minus the water and the fiber. It should also have been harvested at the peak of nutrition, not the peak of flavor and taste. The plant concentrates contain all the phytonutrients that are contained within the plant, and that includes not only the flavonoids that were the subject of this study, but all of the other types of phytonutrients that we need on a regular basis.

The plant concentrates may be found in multivitamin-minerals, as part of a fruit-and-vegetable concentration, or maybe even as a stand-alone. We’re not talking about treating diseases with these supplements; we’re talking about getting the nutrition that you’re supposed to be getting from the foods that you eat (but you’re not). To me, this study pretty much proves that everyone needs to take supplements with plant concentrates every day. They provide good backup while you work on improving your diet.

The Bottom Line

If you want the best chance at preventing degenerative diseases, you need optimal nutrition. That starts with what you eat, including all those phytonutrient-containing vegetables, fruits, beans, grains, and aromatic herbs used to season your food. As a backup, take supplements that contain plant concentrates to complement your diet. It’s not either/or; it’s using them both to get to better health.

Paula and I will be taking some time off to work on more jobs around the house. We’ll be back after a short break.

What are you prepared to do today?

        Dr. Chet

Reference: J Nutr 2020;150:2147–2155.

Can Fasting Reduce Inflammation?

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In this Memo, I’ll review the third paper from the recent journal Cell on fasting and summarize what this all may mean for the use of intermittent fasting.

Researchers used both mice and humans as subjects in a series of studies. The objective was to examine how the immune system responded to a fasting protocol. For the study in humans, the subjects fasted for 19 hours after eating, with blood samples taken before and after the fast. In the mice, a variety of protocols were used. The most common was mice were fed for a short time before food was withheld for the remainder of 24 hours.

In mice and humans, circulating monocytes were reduced. This was important because they were pro-inflammatory in nature; thus inflammation decreased in response to the fasting protocol. In some of the studies, this reduction was maintained even with exposure to pathogens. That means the immune response was not compromised even in animals with induced autoimmune diseases.

Fasting Protocols

Three different studies used at least three different approaches to fasting. In the first study, food was withheld completely for 36 hours. In some phases of the second study, calories were reduced by 50% although the vitamins, minerals, and protein were maintained at normal levels. The final study used a fasting protocol we’re most familiar with: eat within a few hours and liquids only the remainder of the day.

The results were similar in sustaining and perhaps improving the immune system of the animals when placed under pathogenic stress. The only issue is what form of dietary restriction worked best? You can’t ask mice how they felt; you can only check immune system markers. In one of the approaches, the skin of the mice was injured at different times of continued fasting. The healing ability continued until the fast went beyond 48 hours; after that wound-healing was impaired.

The Bottom Line

These studies haven’t changed my approach to fasting. If you’re going to fast to rejuvenate your immune system, don’t play games. Reduce caloric intake to 500 to 800 calories per day for two to three days; those studies show the best benefit. Be sure to select small quantities of the healthiest foods.

Fasting is not abstinence. The current approaches to intermittent fasting are really intermittent abstinence. The idea is to abstain from food completely for 12 to 18 hours while still drinking liquids. That may not be possible for everyone. Some medications have to be taken in relation to food intake. Pre-diabetics and type 2 diabetics should still monitor blood sugar, especially if exercising during the fasting times. The current intermittent fasting approach is more about controlling when you eat than anything else, and that’s something you should do anyway.

I believe in fasting. That’s why I wrote Real-Life Detox—so you could do it right and gain the most benefit. The critical thing is to find a way to eat that you can sustain for the rest of your life, and that includes occasional fasts.

Eat less. Eat better. Move more. That’s always the goal.

What are you prepared to do today?

        Dr. Chet

References:
1. Cell. 2019. DOI:https://doi.org/10.1016/j.cell.2019.07.047.
2. Cell. 2019. DOI:https://doi.org/10.1016/j.cell.2019.07.049.
3. Cell. 2019. DOI:https://doi.org/10.1016/j.cell.2019.07.050

Fasting and Immune Function

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Intermittent fasting is the latest health fad. When I say fad, I mean there are as many definitions of what it means as there are experts. In a recent edition of the journal Cell, three papers were published that provided some insight into the effects of three different types of intermittent fasting on three different systems involved in immune function. That’s our topic of the week. I’ll present each study and comment on the implications on Saturday.

In the first paper, researchers used juvenile mice to examine changes in immune function in sections of the intestine called Peyer’s patches (PP). These patches form an important part of the immune system by monitoring intestinal bacteria populations and preventing the growth of pathogenic bacteria in the intestines. The mice were fasted for 36 hours. Results were compared with normally fed mice that served as controls.

During fasting, immune cells were disrupted and thus compromised the typical immune response; specifically, B cells were sent to bone marrow. It’s difficult to say whether this is a protective mechanism or not. The B cells were returned to the PP during re-feeding. There were many more parts of the study, but the bottom line was that the immune system was compromised during fasting and remained impaired for a time after re-feeding.

We’ll take a look at the second study on Thursday.

What are you prepared to do today?

        Dr. Chet

References:
1. Cell. 2019. DOI:https://doi.org/10.1016/j.cell.2019.07.047.
2. http://bit.ly/2lxYIRa.

How Methionine Affects Cancer Treatment

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If you’ve ever been diagnosed with cancer and you start searching the Internet, one of the things that you’ll come across is using a vegetarian diet to help treat the cancer. I’ve recommended it myself combined with conventional treatment. The question is why? Yes, the phytonutrients from plants are healthier, but is there something in animal products that’s detrimental?

A research group examined the impact of the amino acid methionine on a pathway of one-carbon metabolism; this pathway is the target of a variety of cancer interventions that involve chemotherapy and radiation. They demonstrated that removal of methionine from the diet of mice and humans resulted in more effective treatment in two types of cancer. Chemotherapy and radiation were more effective in both types of cancer once the diet was changed.

There are a couple of important points. First, this was tested on only two types of cancer. There’s no reason to think it would benefit every type of cancer treatment because this one-carbon pathway is not a target for every treatment. Second, because methionine is found in all meat and seafood, it would mean giving up all meat for the duration of treatment.

For myself, I’d give up meat and seafood during treatment whether we have the research or not. It wouldn’t have to be forever and combined with giving up refined carbs to reduce the risk of C diff, it could lead to a better chance for treatments to work. And that’s the key. It’s not in place of treatment; it’s combined with treatment. The goal is to put the odds in your favor. This seems like a simple way to do that.

What are you prepared to do today?

        Dr. Chet

Reference: Nature Vol 572: 397–401 (2019).

Fearsome Twosome: C. Diff and Clade A

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Clostridioides difficile, C. diff for short, is a serious bacterial infection typically acquired after antibiotic treatment in a hospital. Antibiotics disturb the microbiome balance, and as a result, a bacterium that typically may not be a threat becomes one. But C. diff is not just a single bacterium.

In a recent paper, researchers from London sequenced and compared the DNA of 906 strains of C. diff—906! They reported that 761 strains came from humans living in 33 countries. They found that C. diff is still evolving. In fact, one species has adapted to living in hospitals; the type of C. diff that seems to dominate has been termed Clade A. It didn’t develop overnight; it took many years, but it developed specifically for the hospital environment.

Clade A has two characteristics that are a problem for us. It’s resistant to anti-bacterial cleaning products and therefore survives after cleaning. Even more critical is that this form of C. diff has developed the ability to use sugar as a fuel. The researchers actually tested modifying the diets of mice exposed to Clade A and found that it thrived with a sugary diet.

Where does that leave us? I think that further research should explore changing the typical hospital diet including elimination of sugars and simple carbohydrates. The cleaning part is more complicated. Heat will kill it, but that applies to only hospital instruments; for instance, you can’t heat a door handle or a bed’s handrail or to a high enough temperature to kill bacteria. A different solution must be discovered.

For now, in addition to the normal antibacterial precautions, I think it’s smart to greatly limit simple carbs post-surgery or when you’re spending a lot of time in a hospital.

What are you prepared to do today?

        Dr. Chet

Reference: www.nature.com/articles/s41588-019-0478-8.

Should Your DNA Guide Your Diet?

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In an opinion piece, a college professor in the U.K. who had written about personalized nutrition wanted to find out whether she should change her diet based on her genetic profile. She decided to send her DNA to Norway for analysis.

Her genetic profile indicated that she was at risk for having high cholesterol and an increased risk for cardiovascular disease. To deal with that, she became a vegetarian. She also takes high levels of B vitamins because she doesn’t process one of the B vitamins very well. Her point was that knowing her genetics gave her the motivation to take control of her diet and lifestyle. She now advocates that all of us should take control of our health through personalized nutrition based on our DNA analysis.

I’m not so sure. I think genetics are one piece of a complex puzzle. What causes the genes to express themselves? What turns them off? More than anything, what role does the microbiome play when combined with the genes? We still don’t know the answers to any of those questions.

Someday we may be at a point where we can be very specific about nutrition, but we’re not there yet because we not only don’t know the answers—we don’t know the correct questions to ask. For reliable results, it still comes down to what I always tell you: Eat better. Eat less. Move more.

What are you prepared to do today?

        Dr. Chet

Reference: http://bit.ly/2ZclpII

Looking for Single-Nutrient Solutions

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As you might expect, I get asked a lot of questions about health, especially diet and exercise. One of the similarities between questions is whether a specific nutrient is special or unique. When I do the research to learn about the nutrient, I’ve never found one that’s the be-all and end-all—not turmeric or echinacea or omega-3 fatty acids or anything else. Can they be beneficial? Absolutely. But they’re a finishing touch, not a foundation.

The foundation of health begins with vegetables, fruits, whole grains, quality protein, and the best oils. The foundation also includes basic supplementation such as a multivitamin-multimineral and probiotics, among others. If you don’t begin with the best diet, then specific nutritional gaps, whether due to food preferences or genetic issues, can’t be bridged effectively because the body isn’t built on a strong foundation. Once you build your foundation, some of the specific nutrients can fill in gaps and act as insurance for the days you can’t eat as well as you know you should.

Eat better. Eat less. Move more. Build a foundation and you might find miracle nutrients aren’t really necessary.

What are you prepared to do today?

        Dr. Chet

P.S. Paula and I wish all of you a happy Memorial Day weekend! Travel and celebrate safely, and we’ll see you back here on Tuesday.