Tag Archive for: dental caries

Dental Cavities Are an Engineering Wonder

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Continuing our look at the process of dental decay, the methodology for this study was complex to say the least: preserving the plaque, analyzing the structure, obtaining samples of the bacteria, attempting and succeeding to grow the structures on enamel surfaces that mimic teeth, getting photographs of the electronic polymeric structure, and more.

This study demonstrated that the Streptococcus mutans bacterium doesn’t merely attach to the biofilm and multiply; it organizes itself and other bacteria into dome-like structures in order to protect the most inner part of the dome. They tested this by exposing the teeth to a commonly used anti-bacterial rinse and found only the most exterior part of the dome was destroyed. The bacteria then reorganized themselves and the other bacteria so they could continue the attack that causes tooth decay. As long as the medium is present, in spite of treatment, the bacteria will continue to organize its structure to promote decay. Amazing.

What was the conclusion? There was none at this point because this is new research. I have one for you that isn’t controversial nor does it require anything that you probably already don’t do intermittently: cut out a sugary diet for your children and yourself to stop the constant feeding of the bacteria. Then brush regularly after every meal; teach your kids to swish with water after every popsicle or gummy bear. And to break up the plaque, floss every day. That seems to be the only way to address this oral bacterium that’s an engineering marvel.

What are you prepared to do today?

        Dr. Chet

Reference: doi.org/10.1073/pnas.1919099117

Investigating the Architecture of Cavities

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Have you ever wondered how your kids get cavities or why you got them as a kid? As I was researching studies on the microbiome, I found a fascinating article on cavities.

Cavities, also called dental caries, are a disease caused by bacteria that attack the biofilm known as plaque and damage the enamel of the teeth by creating an acidic atmosphere. In addition to the bacteria, cavities are also dependent on diet. All that stuff about sugar causing tooth decay? Yes, it’s actually true—just maybe not in the way we thought. The primary bacterium associated with tooth decay is Streptococcus mutans, an aggressive plaque builder and acid-producer. But how?

Researchers from two universities wanted to examine any types of structures that might be built on teeth by S. mutans and other bacteria that might contribute to cavities. What kind of structures are we talking about? No one really knew for sure. But to find out, they needed to study the structures as close to the mouth as possible but not actually in the mouths of children; they used the extracted teeth of children who had so much decay the teeth couldn’t be saved and preserved them for analysis. As unbelievable as it may sound, up to 2.5 billion people, mostly children, are impacted by this type of decay.

We’ll continue this look at the topic on Saturday.

What are you prepared to do today?

        Dr. Chet

Reference: doi.org/10.1073/pnas.1919099117